| Pitcher's Name | Innings |
| Gerrit Cole | 583.0 |
| Justin Verlander | 563.1 |
| Zack Greinke | 403.0 |
| Lance McCullers | 399.0 |
| Wade Miley | 297.0 |
| Charlie Morton | 281.0 |
| Dallas Keuchel | 278.2 |
| Brad Peacock | 267.1 |
| Jose Urquidy | 109.0 |
| Christian Valdez | 108.1 |
| Famber Valdez | 106.0 |
| Roberto Osuna | 56.2 |
| Will Harris | 27.2 |
| Hector Rondon | 24.1 |
| Enoli Paredes | 14.0 |
| Ryan Pressly | 12.0 |
| Andre Scrubb | 7.0 |
| Tony Sipp | 5.0 |
| Joe Smith | 5.0 |
| Cy Sneed | 3.2 |
| Colin McHugh | 3.0 |
| Blake Taylor | 2.1 |
