| Player's Name | At-Bats | Hits | Average |
| J.D. Harris | 3 | 1 | .333 |
| Derek Fisher | 4 | 1 | .250 |
| Michael Brantley | 743 | 164 | .221 |
| Yuli Gurriel | 1450 | 313 | .216 |
| Evan Gattis | 544 | 116 | .213 |
| Jose Altuve | 1523 | 315 | .207 |
| Tyler White | 54 | 11 | .204 |
| George Springer | 1404 | 276 | .197 |
| Alex Bregman | 1479 | 285 | .193 |
| Carlos Correa | 1329 | 254 | .191 |
| Yordan Alvarez | 581 | 109 | .188 |
| Josh Reddick | 1267 | 224 | .177 |
| Marwin Gonzalez | 6 | 7 | .167 |
| Garrett Stubbs | 6 | 1 | .167 |
| Robinson Chirinos | 534 | 84 | .157 |
| Kyle Tucker | 223 | 35 | .157 |
| Tony Kemp | 45 | 7 | .156 |
| Max Stassi | 189 | 29 | .153 |
| Brian McCann | 322 | 49 | .152 |
| Martin Maldonado | 186 | 25 | .134 |
| Myles Straw | 11 | 1 | .091 |
| Aledmys Diaz | 82 | 6 | .073 |
| Jake Marisnick | 537 | 34 | .063 |
| Abraham Toro | 11 | 3 | .027 |
| Taylor James | 7 | 0 | .000 |
| Dustin Garneau | 6 | 0 | .000 |
