| Player's Name | At-Bats |
| Jose Altuve | 1523 |
| Alex Bregman | 1479 |
| Yuli Gurriel | 1450 |
| George Springer | 1404 |
| Carlos Correa | 1329 |
| Josh Reddick | 1267 |
| Michal Brantley | 743 |
| Yordan Alvarez | 581 |
| Evan Gattis | 544 |
| Jake Marisnick | 537 |
| Robinson Chirinos | 534 |
| Brian McCann | 322 |
| Kyle Tucker | 223 |
| Max Stassi | 189 | Martin Maldonado | 186 |
| Aledmys Diaz | 82 |
| Tyler White | 54 |
| Tony Kemp | 45 |
| Myles Straw | 11 |
| Abraham Toro | 11 |
| Taylor Jones | 7 |
| Marwin Gonzalez | 6 |
| Garrett Stubbs | 6 |
| Dustin Garneau | 6 |
| Derek Fisher | 4 |
| J.D. Davis | 3 |
